Polled genetics has been recommended by the AVMA as an alternative to physical dehorning, but the frequency of the P polled allele is very low in dairy cattle, and most sires that carry the dominant P polled alleles have low genetic merit, write Alison Van Eenennaam and Maci Mueller of the University of California at Davis. Gene editing technology could be used to replace the alleles that code for horns with naturally occurring polled P alleles, but the result would be considered a "new animal drug" subject to FDA regulation under draft FDA guidance.
FDA rules might block promising method to produce hornless dairy cows
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