A study in the Annals of Family Medicine showed that 53% of patients who met the American Diabetes Association's screening criteria and were screened with an A1C point-of-care test met the A1C criteria for prediabetes and 10% for diabetes. Researchers reanalyzed their findings using the US Preventative Services Task Force screening criteria for overweight or obese patients, ages 40 to 70, and found a reduction in the number of patients requiring screening and more missed cases of prediabetes and diabetes.
Japanese researchers found that 29.3% of type 2 diabetes patients on basal-bolus therapy had an A1C increase of more than 0.5%, compared with 22.8% of those on once-daily long-acting insulin, 24.9% on twice-daily biphasic insulin and 20.7% on biphasic insulin three times daily. The findings in the Journal of Diabetes Investigation, based on 757 adults with a mean age of 65.7, revealed that those on basal-bolus therapy had significantly lower odds of increasing daily insulin units one year after their regimen than those on biphasic insulin twice daily.
A study in the journal Nature found that the mosquitoes that spread the Zika virus in Florida last year had been circulating in the area about three months prior to infections being reported. Genetic information studies indicated that the Zika virus that spread in Florida mosquitoes mainly came from the Caribbean, researchers said.
Iowa State University researchers found that people whose parents didn't have Alzheimer's disease and who had a longer version of the TOMM40 metabolic gene had about 20% lower odds of developing Alzheimer's and had better memory after as long as a decade, while those with a family history of AD and a longer version of the gene actually had an increased Alzheimer's risk. The findings were published in Alzheimer's & Dementia.
The European Commission granted marketing authorization to Blue Earth Diagnostics' Axumin, or F-18 fluciclovine, for use in PET imaging to detect prostate cancer recurrence in adult men in whom recurrence is suspected after primary curative treatment because of elevated blood prostate-specific antigen levels.
High-sensitivity troponin T outperforms risk scores in the prediction of death and composite end points in patients with stable cardiovascular disease. Therefore, it may be easier and more convenient to use in daily practice.
The authors conducted a retrospective cohort study of all ACE inhibitor prescriptions in the outpatient setting at a large academic center between Jan. 1, 2000, and Sept. 30, 2008, using data derived from electronic health record (EHR) sources. Among 134,945 patients prescribed ACE inhibitors, 0.7% (n=888) developed angioedema during the subsequent five years. Sex was similar, but patients who developed ACE inhibitor angioedema were younger (61.5 vs. 62.7 years, p=0.007) and more likely to have a history of NSAID allergy compared to patients who didn't develop angioedema (7.1% vs. 4.2%, p<0.001). The incidence of ACE inhibitor angioedema within a large EHR is consistent with large clinical trial data. Some risk factors were identified, but underlying genetic and pathophysiological mechanisms require further study.
This study investigated the prevalence of six aspects of father involvement in delivery and child care, exploring their associations with intimate partner violence (IPV) against women as well as paternal health in an Asia-Pacific context. In 6,184 fathers, the prevalence of different aspects of father involvement ranged from 40.0% to 62.9%. Presence at prenatal visits, taking paternity leave, and helping children with homework were associated with a reduced likelihood of IPV against women. Father involvement accounted for 2% of the variance of men's perceived health, 4% of depression, and 2% of life satisfaction.
Young people who were exposed to electronic nicotine delivery systems (ENDS) through use, advertising, or living with ENDS users had more accepting attitudes toward cigarette smoking and were more open to trying cigarette smoking.
With increasing societal awareness of the prevalence and impact of acute pain, there is a need to develop an acute pain classification system that both reflects contemporary mechanistic insights and helps guide future research and treatment. This Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks effort provides a much-needed standardization of clinical diagnostic criteria, which benefits clinical care, research, education, and public policy.
- Page 1