The PDD Blue Light Flexible Video Cytoscopy System has been launched by Karl Storz for use in the detection of bladder cancer. The release followed the recent FDA approval of a supplemental new drug application and a premarket approval supplement to add use of the cytoscopy system to the indication of the company's Blue Light Cystoscopy with Cysview.
Patients with malignant pheochromocytomas and paragangliomas had significantly reduced tumors in the lungs, liver and lymph nodes, significantly increased progression-free survival, better blood pressure and diabetes remission after receiving cabozantinib, researchers reported at the American Association of Clinical Endocrinologists' annual meeting. The findings also showed that cabozantinib stabilized disease among five of eight patients with predominant bone metastases on FDG-PET scans and was well-tolerated among all patients.
A German study in the Journal of Nuclear Medicine showed that a breakthrough method combining PET/CT and a physiologically based pharmacokinetic/dynamic model using Lu-177 PSMA for imaging and therapy yielded a one plus or minus 40% relative deviation of predicted and measured tumor volume among patients with metastatic castration-resistant prostate cancer undergoing radioligand therapy, indicating the approach's feasibility and acceptable accuracy. "Future work including a refined model, definition of subpopulations and use of SPECT/CT data will help to improve further the prediction accuracy of the model," researchers wrote.
Two clinical studies evaluating JNJ-54861911, or atabecestat, for Alzheimer's disease were stopped by Johnson & Johnson's Janssen Biotech because of an unfavorable risk-benefit profile for the beta-site amyloid precursor protein-cleaving enzyme inhibitor. Screening, randomization and dosing of atabecestat will be stopped by the company in a Phase IIb/III study in patients with late-onset preclinical-stage Alzheimer's and in a midstage European long-term safety study.
China's State Drug Administration accepted under priority review status Innovent Biologics' new drug application for IBI308, or sintilimab, which is being developed as a treatment of relapsed or refractory classical Hodgkin lymphoma. In a midstage trial, the candidate achieved a disease control rate of 97.9% and an overall response rate of 79.2%.
There was a more than 10% increase in compensation for primary care physicians during the past five years, with the increases in median pay differing significantly across US states, according to a report from the Medical Group Management Association. Wyoming had the largest increase in physician compensation at 41%, followed by Maryland at 29%, Louisiana at 27%, Missouri at 24% and Mississippi at 21%, while physicians in the District of Columbia were paid the least with $205,776 in median total compensation.
A report from the Robert Wood Johnson Foundation and the Urban Institute estimates that 4.5 million people would gain health care coverage if the 19 states that have not fully expanded Medicaid did so next year. The move would raise federal health care spending as much as $37.8 billion, while state Medicaid spending would grow as much as $3.0 billion, but the additional spending would be completely or mostly offset by savings in other areas, the report indicates.
Artificial intelligence can help radiologists curb administrative tasks and increase patient interaction, as well as address increasing volumes of radiological interpretations, limited autonomy, uneven distribution of work and declining reimbursements, but they should combine the technology with their talent to yield these benefits, according to a Deloitte paper. "With new technologies and diagnostic capabilities, radiologists will need to learn new skills and capabilities to adapt," researchers wrote.
Registered dietitian Sunetra Rangraj developed and oversees an eight-week culinary training program for at-risk young people to prepare them for jobs in New York City. Rangraj runs the program through The Door, a youth-development center for people ages 12 to 24.
To minimize the risk of developing unhealthy food obsessions from social media, registered dietitians say people should unfollow accounts that make them feel bad about themselves and follow people who promote balance and a positive message. Registered dietitian nutritionist Rebecca Scritchfield said people should not compare themselves to other people on social media.