A retrospective cohort study in JAMA Internal Medicine conducted by researchers from the Karolinska Institutet in Sweden found that the age and gender of the donor of blood transfusions had no effect on the survival of recipients. The findings were based on data from 968,264 Scandinavian patients. The methodology used -- similar to that of a large Canadian study which found an age/gender association with outcomes -- highlights "the importance of extreme caution in assessing epidemiologic analyses in this field," according to the authors.
The deadly Ebola outbreaks in Western Africa taught the global health community many lessons about the lack of preparedness to battle devastating pathogens, and one of the key lessons was the need for a ready vaccine that could stem the potential loss of lives and its effect on a country's economy, write J. Stephen Morrison and Chris Millard of the Center for Strategic and International Studies. The launch of the Coalition for Epidemic Preparedness Innovations is a step in the right direction that allows governments, health practitioners and drugmakers a chance to forge partnerships to facilitate a more rapid response to future global health threats.
Marvin Smoot received transplanted tissue to repair a torn anterior cruciate ligament, and he knows his donor was named Brian and lived in California. "The gift they gave me was the ability to play football again," said Smoot, adding that the transplant has had an impact on "everything I do in my life."
Portland Trail Blazers center Festus Ezeli is recovering from knee surgery in March, hoping he can play again in the NBA and preparing to thank the family of whoever donated his transplanted ligament. "I'm actually working on my letter right now, because I really do want to meet them," said Ezeli, who is 6 feet 11 inches tall.
Rear Adm. Sylvia Trent-Adams will serve as acting surgeon general after Vivek Murthy was "relieved of his duties," according to an HHS statement. Trent-Adams has served the Public Health Service Commissioned Corps for 24 years and was chief nurse officer of the corps.
Hemoglobin levels continued to increase with ferric citrate tablets in an open-label extension of a randomized controlled trial of 81 patients with nondialysis-dependent chronic kidney disease and iron deficiency anemia. Serum ferritin levels increased by 48.2 ng/mL during the trial and 72.6 ng/mL during the extension period. The results were reported at the National Kidney Foundation Spring Clinical Meetings.
All women, regardless of their ethnic background, should be offered additional carrier screening before pregnancy, according to a new opinion from the American College of Obstetricians and Gynecologists' Committee on Genetics.
"[T]he pretest probability of being a carrier for a specific disorder may not be consistent with previous assumptions about the prevalence of that disorder in the various ethnic and racial groups with which a patient identifies," the opinion states.
Today is World Malaria Day, and this year's theme is "End malaria for good." The World Health Organization announced that a malaria vaccine will be studied starting in 2018 in Ghana, Kenya and Malawi in trials involving 360,000 children.
Investigators with the University of California at Los Angeles reported in the American Journal of Tropical Medicine and Hygiene that 7 of every 10 US travelers who contract malaria require hospitalization. The researchers estimated that the US has 2,100 annual cases of malaria, which is higher than CDC estimates of 1,500 to 2,000 cases.
A restructuring at Immune Pharmaceuticals could result in the spinoff of Cytovia, its oncology subsidiary, to develop therapies for immuno-oncology and hematologic diseases. Daniel Teper, CEO of Immune Pharma, will go with Cytovia.
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