Alnylam Pharmaceuticals is Luke Timmerman's pick for comeback player of 2013 after settling early disputes and forging ahead with RNA interference drugs. Ironwood Pharmaceuticals is a wild card as it awaits market response to its irritable bowel syndrome drug, and Hyperion Therapeutics is living up to early promise to become rookie of the year, Timmerman writes. He picks Alkermes for "steal of the draft" award and Clay Siegall of Seattle Genetics for manager of the year.