Researchers looked at folic acid and vitamins B6 and B12, which are believed to lower homocysteine in the blood, and found giving high vitamin doses to patients who previously suffered strokes had no effect on whether they had new strokes or heart problems or died. The published report did note those at the study's start who had high levels of homocysteine, an amino acid believed to contribute to heart disease, were most likely to suffer a second stroke.

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