A study indicates the antidepressant nortriptyline used with a nicotine patch doubles a smoker's chances of quitting smoking, and the research team says the combination may prove to be a useful alternative when other first-line therapies have failed. The team noted the antidepressant did not seem to ease withdrawal symptoms in their study of 158 adult smokers treated with the antidepressant or a placebo in addition to the patch.

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