Tioga Pharmaceuticals says its investigational oral kappa opioid agonist, asimadoline, gave modest relief to patients with irritable bowel syndrome who had moderate to severe pain and diarrhea. Trials show the drug did not benefit people with constipation-predominant IBS or patients with only mild pain.
Patients at high risk for colon cancer are less likely to undergo repeat colonoscopies to spot precancerous growths, according to a new study. A second study found colonoscopy continues to be the best first-line method of detecting polyps.
An investigational drug called AT-1001 may protect celiac disease patients by preventing gluten from crossing the intestinal mucosa, one study found. In a second study, investigators said the criteria for diagnosing the disease may be too narrowly focused, missing many patients who should get treatment.