Spanish researchers say people with chronic obstructive pulmonary disease may be predisposed to getting acid reflux, but GERD patients generally are no more likely to get COPD than other people. One study shows people with COPD had a 46% higher incidence of GERD. A second study finds COPD did not occur any more frequently among GERD patients than among other populations.
There is a shortage of injectable leucovorin, a common agent used with chemotherapy in treating colorectal cancer patients. Leucovorin is a form of a B vitmain that improves the effectiveness of 5FU, which is a standard colon cancer treatment. FDA says the shortage is caused by "manufacturing delays" but details and an estimated timetable for new shipments remain unknown.
A meta-analysis found people who had smoked at some point in their lives were 18% more likely to develop colorectal cancer than those who had never smoked and 25% more likely to die from it. Researchers say smoking is a factor physicians should consider when deciding at what age a person should begin having colorectal cancer screening.
Drinking lots of clear liquids can help reduce the risk of kidney damage from bowel preps used prior to a colonoscopy. The Food and Drug Administration recently issued "black box" warnings for two popular preparations -- OsmoPrep and Visicol -- because of the risk of kidney disease and plans to make them available only by prescription. Another way to reduce the risk of problems is to select an alternative to oral sodium phosphate products, such as bowel cleansers that use polyethylene glycol.
A study finds maslinic acid from olive-skin pomace can inhibit cell proliferation and cause the apoptotic death of colon cancer cells. International researchers say natural chemo-preventive agents might be a less expensive yet effective way of treating colon cancer. Low concentrations of maslinic acid are found in plants with medicinal properties, but its concentration in the waxy skin of olives may be up to 80%.