PerkinElmer is developing silicon photomultipliers for combined PET/MRI applications. SiPMs' advantage over photomultiplier tubes, the standard for PET, is that they are not affected by magnetic fields. "SiPMs as solid-state detectors are a further step toward high-definition combined MRI/PET imaging," said a PerkinElmer official.
An international team of researchers used nuclear magnetic resonance spectroscopy to conduct a genetic-association study involving more than 17,000 women and found 43 genetic loci linked to lipoprotein metabolism, including 10 new ones. Lipoprotein profiles are an important part of cardiovascular risk, and this study's methodology could help provide a better picture of these profiles.
Molecular-imaging firm Gamma Medica-Ideas has received an Innovation Award from the World Congress on Medical Physics and Biomedical Engineering for the development of a prototype SPECT/MRI imaging system. "This breakthrough could significantly impact the future of medical imaging across many fields. An example where it could make an impact is in the diagnosis of vulnerable plaque," said the company's research director.
Singaporean researchers have developed a fluorescent compound, called glucagon yellow, that can be used for prolonged live-cell imaging of glucagon, a hormone that influences the development of pancreatic diseases. The researchers are looking to convert the dye into PET and SPECT imaging agents for use in animal and clinical studies.
A study involving advanced biliary-tract cancer patients showed that combining bevacizumab with gemcitabine and oxaliplatin treatment improved disease management and increased progression-free and overall survival. Scans using 18FDG-PET showed a drop in maximum standardized uptake value following two treatment rounds, which helped predict progression-free and overall survival.