Children with sickle cell disease who got H1N1 flu were three times more likely to have acute chest syndrome, with lung inflammation, reduced oxygen capacity and shortness of breath, than those with seasonal flu virus, a study found. The Johns Hopkins Children's Center team said H1N1 patients also were five times more likely to be admitted to an ICU and also were more likely to need a blood transfusion and be put on a ventilator.

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