A study in Diabetes Care found insulin dose requirements for people with complication-free type 1 diabetes decreased by 14.2% at altitudes up to 5,000 meters, compared with sea level, but glucose levels and acute mountain sickness symptoms increased at altitudes above 5,000 meters. "In individuals with type 1 diabetes, insulin requirements tend to increase during very high altitude trekking despite high energy expenditure and reduced caloric intake," researchers said.

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