Obese patients and type 2 diabetes patients with heart failure appeared to have greater accumulation of large amylin oligomers, fibrils and plaques compared with participants with normal hearts or those with heart failure who were not obese or did not have diabetes, a study in Circulation Research found. Inhibiting the circulation of large amylin oligomers from the pancreas to the heart may help predict and prevent the onset of heart failure in people with prediabetes, a researcher said.

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