A study published online in the Canadian Medical Association Journal found that oral bisphosphonate use increases first-time users' risk of developing uveitis and scleritis compared with nonusers. Researchers studied 934,147 patients and found that the incidence of uveitis in first-time bisphosphonate users was 29 per 10,000 person-years versus 20 per 10,000 in nonusers, while the incidence of scleritis was 63 per 10,000 person-years in first-time users versus 36 per 10,000 in nonusers.

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