Canadian researchers assessed almost 3,900 10th-graders in Quebec and found that users of either ecstasy or methamphetamine and/or amphetamine had a 60% to 70% higher risk of showing depressive symptoms a year after last use compared with nonusers. They also found that those who tried both party drugs had a twofold higher risk of depression than nonusers. The study was published in the Journal of Epidemiology and Community Health.

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