Type 2 diabetes patients with mild nonproliferative diabetic retinopathy who developed clinically significant macular edema showed higher average microaneurysm turnover than those who did not develop CSME, according to a study in Diabetes Care. Researchers also found an MA turnover value of nine or higher had a 57.7% sensitivity and an 81.2% specificity in forecasting CSME onset within two years.

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