The U.S. Preventive Services Task Force found that evidence regarding vitamin D and calcium supplementation at high doses for fracture prevention is not clear enough for the task force to make a recommendation. However, evidence indicates there is no benefit to taking vitamin D and calcium at low doses to prevent fractures among postmenopausal women. There was little harm associated with low doses of the supplements, but possible risks include an increased likelihood of kidney stones. Read the USPSTF fact sheet.

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