A mouse's brain with its entire intact network of interconnections can now be studied using a new method, dubbed Clarity, developed by Stanford researchers. The feat is achieved by withdrawing all the brain's lipids -- which block chemicals and light -- while leaving the brain's structures undisturbed. "Clarity promises to revolutionize our understanding of how local and global changes in brain structure and activity translate into behavior," commented Paul Frankland, a senior scientist in neurosciences and mental health at the Hospital for Sick Children Research Institute in Toronto.

Related Summaries