A study published in a cardiology journal comparing SPECT/CT and cardiac-computed tomography angiography for diagnosis of coronary artery disease found that SPECT/CT performed better. "The key difference between SPECT and CCTA lies in the ability of SPECT to detect myocardial ischemia," researchers wrote. "It is this ability that allows clinicians to make meaningful changes in management, which in turn leads to better patient outcomes, an essential component of value in health care."

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