Texas cardiologist Joseph Quintana treats chronic total occlusions, one of the most serious conditions associated with peripheral arterial disease and one that can lead to amputation, by inserting a thin wire into the occluded artery and vibrating the tip 20,000 times a second to penetrate the blockage. He can then employ balloon angioplasty or a stent to restore blood flow. The device, called the Crosser Catheter, claims a success rate of more than 80%.

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