Data presented at an Alzheimer's disease conference reveal an association between subjective cognitive decline and development of Alzheimer's disease. Four research teams reported similar findings that patients with self-reported concerns about memory and cognition showed greater risks of developing mild cognitive impairment or dementia later in life. One study conducted PET scans using amyloid tracing agent C-11 Pittsburgh Compound B and found that patients who expressed concerns about their cognitive function showed more evidence of beta-amyloid protein buildup than patients who did not report memory concerns.

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