Investigators from the Scripps Research Institute created a compound that increased activation of the protein REV-ERB in obese mice, which lost weight while on a high-fat diet and used more energy, even without exercise. Thomas Burris, co-author of the study in Nature Medicine, said the compound "seems to act as an exercise mimic" and holds promise that it could someday help people with disabilities or others who cannot exercise get the health benefits of a workout minus the physical exertion.

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