Campaigns to fight antibiotic resistance must carefully consider which antibiotics should be used less, according to a study in the journal Antimicrobial Agents and Chemotherapy. Researchers at the Conservatoire National des Arts et Metiers in Paris have developed a mathematical model of methicillin-resistant Staphylococcus aureus circulation to assess simulations of antibiotic use reduction. "We found that the reduction in MRSA hospital rates could have been much larger than it actually was following the 2002 antibiotic reduction campaign. Our results also suggest that changes in the distribution of antibiotics prescribed for nonhospitalized patients actually limited the impact of the antibiotic reduction campaign in French hospitals," study author Laura Temime said.

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