A study compared aspirin and low-molecular-weight heparin for cost-effectiveness as a prophylactic measure for patients with no history of venous thromboembolism undergoing total hip arthroplasty and total knee arthroplasty. Aspirin was cost-effective following total hip arthroplasty as well as after a total knee arthroplasty for patients who were age 80 and older. Researchers were unable to determine its cost-effectiveness for the knee procedure when patients were younger than 80.

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