In a study published in the Journal of Nuclear Medicine, FDG-PET/CT appeared to be effective in detecting differentiated thyroid carcinoma lesions that traditional protocols failed to identify. Researchers evaluated 18F-FDG-PET/CT findings in patients simultaneously receiving I-131 therapy and found additional tumors in up to 46% of the patients. "F-18 FDG PET/CT is useful for the detection of recurrent DTC lesions, especially in patients with iodine-negative tumors and elevated serum thyroglobulin levels," according to researchers.

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