The Mayo Clinic and the city of Rochester, Minn., intend to transform the area into a global health destination. Tina Smith, chief of staff for Gov. Mark Dayton, was chosen to head the board of directors that will oversee its makeover. The $6 billion project will be developed through a public-private partnership over the next two decades. A design master plan is expected to be completed by the first half of 2014.

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