Researchers at the University of Toronto and Massachusetts General Hospital proposed a new approach in treating atherosclerosis, a disease that disrupts the flow of blood around the body and could lead to cardiovascular complications. The study re-evaluated previous assumptions that cells outside the plaques called monocytes cause atherosclerosis progression and suggested that targeting the proliferation of new macrophages within plaques may be a better approach in the treatment of the disease. Findings, published in the journal Nature Medicine, were based on mouse subjects.

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