U.S. researchers followed almost 1,100 children with hypertrophic cardiomyopathy for 19 years and found that those with inherited metabolic problems or a combination of hypertrophic cardiomyopathy and other cardiomyopathy phenotypes had worse outcomes. Congestive heart failure, diagnosis at a younger age, lower weight, and symptoms of abnormal left ventricle structure or function were linked to increased odds of dying. Patients with two or more of these risk factors were at greater risk of dying or heart transplant, according to the study presented at the European Society of Cardiology meeting and published in The Lancet.

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