The use of low-calorie, artificial sweeteners may actually lead to weight gain because they do not satisfy the body's craving for sugar, which in turn may prompt people to consume more sugar-laden foods, a study says. The findings in the Journal of Physiology demonstrate "how physiological states may impact on our choices between sugars and sweeteners," and suggest that using a combination of sweeteners and minimal amounts of sugar may help maintain energy metabolism, said lead researcher Ivan de Araujo.

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