Subthreshold bipolar I disorder symptoms and emotional dysregulation were associated with the highest odds of bipolar I disorder conversion in children with attention-deficit/hyperactivity disorder and major depressive disorder, a study showed. Children with subthreshold symptoms were more than nine times more likely to convert to bipolar I, while those with impaired emotional regulation had a more than twofold increased conversion risk, researchers reported in the Journal of Affective Disorders.

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