High-risk organ donors who tested negative for hepatitis C virus in pretransplant nucleic acid tests still should undergo screening and monitoring to lower the chances of transmission to organ recipients, according to research presented at an infectious disease conference in San Francisco. Two recipients diagnosed with genotype 2b HCV after transplant were found to have acquired the virus from a donor whose splenocytes tested positive for HCV RNA only on the day of the transplant, indicating a recent infection.

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