Patients with Philadelphia chromosome-positive acute lymphoblastic leukemia who underwent single-cord blood transplantation had a higher overall survival rate of five years, according to research published in the journal Hematologica. Evaluation results involving 45 patients with Ph+ALL who underwent transplantation from unrelated donors showed lower incidence of graft-versus-host disease and higher mortality rate associated with treatment on day 100 and at five years. Researchers suggest further studies to develop ways of reducing relapse after transplant.

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