12/27/2013

Patients with mild cognitive impairment and a history of head trauma are more likely to have increased beta amyloid in the brain, an ongoing study suggests. Among 141 patients in the Mayo Clinic Study of Aging who underwent PET imaging, 25 people with MCI and a history of head trauma had beta amyloid plaques that were on average 18% higher than those with no history, according to findings in the journal Neurology. "The association between head trauma and amyloid appears only in the MCI group because amyloid is a byproduct of the myelin repair process and occurs only after a critical level of demyelination has occurred," researchers said.

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