Overall, vaccines have prevented an estimated 103.1 million cases of diphtheria, hepatitis A, measles, mumps, pertussis, polio and rubella since 1924, according to a report published in the New England Journal of Medicine. Of the seven contagious diseases, measles had the fastest drop in number of cases following the introduction of the vaccine, while diphtheria recorded the biggest decline in cases after the vaccine was introduced.

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