Women who become pregnant within 12 months of a common procedure to treat precancerous cervical cell changes are at significantly increased risk of spontaneous abortion, concludes a new study in Obstetrics & Gynecology. The findings, say the authors, could help health care providers advise women regarding timing for pregnancy after a loop electrosurgical excision procedure. The researchers evaluated data for 596 women who underwent LEEP and subsequently became pregnant during a multicenter study from 1996 to 2006. Women who became pregnant fewer than 12 months after the procedure were 5.6 times as likely to abort spontaneously at fewer than 20 weeks after adjusting for potential confounding factors than were women who conceived a year after LEEP. The shorter the LEEP-to-pregnancy interval, the higher the risk of spontaneous abortion. No increased risk for preterm birth was identified among women with a history of LEEP. Read the article.

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