Baseline severity at rest predicts response duration for the treatment of lateral canthal lines with onabotulinumtoxinA, while patient age and wrinkle severity at maximum smile as well as at rest predict meaningful clinical response, according to research presented at the ASDS Annual Meeting. Treatment of crow's feet improved patients' perceptions of attractiveness, fatigue and age, and those whose glabellar lines were also treated had even higher satisfaction levels.

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