This case illustrates the unique clinical course of a patient with a severely calcified, mildly stenotic aortic valve and concomitant hypertrophic cardiomyopathy. She had rapid progression of aortic stenosis after treatment for her dynamic left ventricular outflow gradient. Both entities have comparable symptoms and elevated left ventricle to aortic gradients, with valvular aortic stenosis having a fixed orifice and hypertrophic cardiomyopathy a dynamic left ventricular outflow tract gradient. The understanding of the interaction between these two separate yet mimicking conditions continues to evolve.
This study concluded that in athletes with left ventricular (LV) hypertrophy in the "gray zone" with hypertrophic cardiomyopathy (HC), LV cavity size appears the most reliable criterion to help in diagnosis, with a cut-off value of <54 mm useful for differentiation from athlete's heart. Other criteria, including LV diastolic dysfunction, absence of T-waves inversion on electrocardiogram and negative family history, further aid in the differential diagnosis.
Male adolescents who continually participate in organized sports have higher odds of medical use and misuse of opioid medications. Male athletes may be at a greater risk to misuse opioid medications because of greater access to these medications. (Full-text access is time limited.)
A study published in the Journal of Nuclear Medicine found that maximal wall thickness measured through PET/CT can be a strong indicator of hypertrophic cardiomyopathy. Maximal wall thickness was linked to impaired peak myocardial blood flow and myocardial flow reserve. The researchers said they did not find a link between left ventricular outflow tract gradients and myocardial blood flow. The results need to be validated in larger trials, the researchers said.