Larry Downing/Reuters

The Senate unanimously confirmed Sylvia Mathews Burwell to lead the Office of Management and Budget, but hearings to confirm her as HHS secretary are likely to be contentious. The Rhodes scholar and Harvard University graduate is known as a detail-oriented manager and, if confirmed, will guide continuing implementation of the Affordable Care Act. White House Chief of Staff Denis McDonough called Burwell "a proven manager and relentless implementer."

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