Researchers examined data on more than 9,800 women in the U.S. and found that the use of clomiphene citrate and gonadotropins does not appear to increase the risk of developing breast cancer. The study did find that women who failed to become pregnant after taking the infertility drugs or who took 12 cycles or more of clomiphene citrate were more likely to develop invasive breast cancer than women who did not take the medications. The increased risk may be related to infertility itself, and continued monitoring is needed, said Louise Brinton of the National Cancer Institute. The findings appear in the journal Cancer Epidemiology, Biomarkers & Prevention.

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