Treating moderately severe non-culprit vessels at the time of primary PCI is associated with lower risk of future major cardiac events, according to results of the PRAMI study presented at the SCAI 2014 Scientific Sessions. Established guidelines recommend against treating non-culprit lesions, but the study found even lesions of moderate severity pose a risk. "You may say, OK, I will only do the really severe lesions," presenter Dr. Keith Oldroyd said. "... But, if you cut it off at 95% to 99%, you will identify only 20% of the subsequent events, and you will miss 80% of the events. If you move the cutoff to 75%, this time you pick up 80% of the events, but you still miss 20%."