Acute kidney injury (AKI) is recognized more frequently in hospitalized children, with the incidence ranging from 4.5% to 82%. In a retrospective cohort study, the authors assessed children exposed to aminoglycoside or nephrotoxic medications for three days or more for AKI. Six months after treatment, 70% of children receiving nephrotoxic medications had evidence of residual kidney damage (reduced estimated glomerular filtration rate, hyperfiltration, proteinuria or hypertension), even though few underwent a complete evaluation for chronic kidney disease.

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