Researchers found that individuals with major depressive disorder, especially those ages 65 and older, had a higher incidence rate of Alzheimer's and non-Alzheimer's dementia, compared with those who didn't have MDD. The findings in the journal Aging & Mental Health also associated stroke, coronary artery disease and elevated Charlson Comorbidity Index scores with higher AD risk, and stroke and hypertension correlated with increased NAD risk.
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