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PET, MRI study links cerebrovascular risk to higher odds of Alzheimer's

Researchers from Columbia University Medical Center who used florbetapir PET and T1- and T2-weighted MRI found that individuals with Alzheimer's disease and mild cognitive impairment had significantly increased amyloid burden but insignificantly higher white-matter hyperintensity volumes, compared with healthy controls, but those with Alzheimer's had the most severe decrease in cortical thickness across all groups. The findings were presented at the SNMMI Annual Meeting.

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