Researchers used whole genome sequencing to find 13 rare gene variants linked to Alzheimer's disease and identified new genetic links between AD and neuroplasticity and the function of synapses, according to a report in Alzheimer's & Dementia: The Journal of the Alzheimer's Association. "This paper brings us to the next stage of disease-gene discovery by allowing us to look at the entire sequence of the human genome and assess the rare genomic variants, which we couldn't do before," study lead author Dmitry Prokopenko.
Researchers discover 13 gene variants linked to AD
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