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Targeting mRNA could prevent Parkinson's progression

A compound that selectively binds to the messenger RNA that encodes alpha-synuclein protein inhibits its translation in cells and could slow progression of Parkinson's disease, researchers reported in Proceedings of the National Academy of Sciences. The researchers used an RNA/protein-matching technology to identify the compound, and study co-author Maral Mouradian says the method could be applied to other neurodegenerative diseases.

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