More than 25,000 people have volunteered with an online recruiter for SARS-CoV-2 challenge trials meant to accelerate approval of a vaccine, but too little is known about the virus to fully inform volunteers of the risks posed and no cure is available, writes Michael Rosenblatt, chief medical officer at Flagship Pioneering and an advisor to Moderna. Any missteps in a human challenge trial could significantly undermine public trust and delay development of an effective vaccine, and a conventional study may be able to be conducted just as quickly, Rosenblatt writes.
Commentary: No need for coronavirus challenge trial
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