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Weight fluctuations tied to worse diabetes outcomes, study finds

Body weight variability was associated with higher risks of death, heart failure, microvascular events and primary outcome event, such as cardiovascular death or nonfatal myocardial infarction or stroke, among type 2 diabetes patients, according to a study in The American Journal of Cardiology. Researchers conducted a post-hoc analysis of the ACCORD trial involving 10,251 patients and found an almost threefold increased risk for a primary outcome event among those who had normal weight at baseline but were in the highest quartile of body weight variability, compared with those with obesity at baseline but remained in the lowest quartile of body weight variability.

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