Compared with adults with normal blood pressure in midlife and late-life, those with midlife and late-life hypertension and those with midlife hypertension and late-life hypotension were significantly more likely to develop dementia, but only those with midlife hypertension and late-life hypotension had increased odds of mild cognitive impairment, researchers reported in the Journal of the American Medical Association. Another study in the same journal involving adults with hypertension ages 50 and older showed smaller increases in white matter lesion volume among those who received intensive BP treatment, compared with those who were given standard treatment.