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DKA-HHS, hypoglycemia, hypokalemia lead to higher mortality risk

A study published in Diabetes Care found that patients with diabetic ketoacidosis and a hyperosmolar hyperglycemic state upon hospital arrival had higher mortality rates, compared with patients who had only DKA or HHS. Using data from 1,211 patients, the researchers also found that DKA-HHS patients who developed hypoglycemia or hypokalemia within 48 hours of hospital admission were 4.8 times and 4.9 times more likely to die, respectively, and suggested that there need to be "effective protocols to closely monitor both glucose and potassium levels during insulin therapy."

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