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Study identifies 2 phases of C-peptide decline in type 1 diabetes

Patients with type 1 diabetes experience two phases of C-peptide decline during the first four decades after diagnosis, with the first phase occurring over a seven-year period followed by a period of stability, researchers reported in Diabetes Care. The findings, based on 1,549 patients, suggest that understanding the two phases' immunologic and pathophysiological differences will improve knowledge of beta cell survival.

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